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Impact of marijuana on venous thromboembolic events: Cannabinoids cause clots in trauma patients

As marijuana use continues to rise across the country, new research is uncovering unexpected health concerns—especially in trauma patients. A study analyzing over 593,000 adult trauma cases from the ACS Trauma Quality and Improvement Program (2015–2016) found a significant link between preinjury marijuana exposure and increased thromboembolic complications (TEC), such as deep venous thrombosis (DVT) and pulmonary embolism (PE). After adjusting for confounding factors, patients who tested positive for THC had nearly triple the rate of TEC compared to those who did not (3.5% vs. 1.1%). Notably, the THC+ group showed higher DVT (6.6% vs. 1.8%) and PE (2.2% vs. 0.2%) rates, though no differences in stroke, heart attack, or mortality were observed.

Key Facts:

  • Population studied: 593,818 adult trauma patients
  • Matched patients analyzed: 678 (226 THC+, 452 THC−)
  • TEC rate: 4.3% overall
  • Higher DVT in THC+ group: 6.6% vs. 1.8%
  • Higher PE in THC+ group: 2.2% vs. 0.2%
  • No significant difference in mortality or stroke risk

 

While marijuana alone may not cause chronic lung diseases like COPD, its impact on trauma patients is worth attention. THC can alter blood coagulation, increasing the risk of life-threatening complications following injury. With marijuana use becoming more widespread, it is critical for clinicians and patients to understand these risks and consider preventive screening for thromboembolic events in THC-positive trauma cases.

 

Reference:https://pubmed.ncbi.nlm.nih.gov/32209959/

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